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CTGF Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR06011G 100 μl / $495

CTGF Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR06011G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CTGF Antibody (C-term).

Molecular Weight

38091 Da

Cellular Localization

Antigen Cellular Localization: Secreted, extracellular space, extracellular matrix. Secreted

Host

Rabbit

Species Reactivity

Human

Immunogen

315-349 aa

Target

This CTGF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 315-349 amino acids from the C-terminal region of human CTGF.

Isotype

Rabbit Ig

Symbol

CCN2, HCS24, IGFBP8

GeneID

UniProt ID

Function

Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.

Summary

Connective tissue growth factor (CTGF), a member of the CCN family of secreted matricellular proteins, regulates fibrosis, angiogenesis, cell proliferation, apoptosis, tumor growth, and metastasis.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Images

All lanes : Anti-CTGF Antibody (C-term) at 1:1000 dilution Lane 1: A549 whole cell lysate Lane 2: NCI-H460 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 38 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with CTGF antibody (C-term) (Cat.APR06011G), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specification

Quantity

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