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S100A6 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR05894G 100 μl / $495

S100A6 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR05894G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality S100A6 Antibody (C-term).

Molecular Weight

10180 Da

Cellular Localization

Antigen Cellular Localization: Nucleus envelope. Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

37-67 aa

Target

This S100A6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-67 amino acids from the C-terminal region of human S100A6.

Isotype

Rabbit Ig

Symbol

CACY

GeneID

UniProt ID

Function

May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative.

Summary

S100A6 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC, E

Dilution

WB~~1:1000 FC~~1:10~50

Images

Western blot analysis of S100A6 antibody (C-term) (Cat.APR05894G) in mouse lung tissue lysates (35ug/lane). S100A6 (arrow) was detected using the purified Pab.

Western blot analysis of S100A6 (arrow) using rabbit polyclonal S100A6 Antibody (C-term) (Cat. APR05894G).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the S100A6 gene (Lane 2) (Origene Technologies).

S100A6 Antibody (C-term) (Cat. APR05894G) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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