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BAR2 Antibody (S261)

Catalog # Availability Size / Price Inquiry
APR05870G 100 μl / $495

BAR2 Antibody (S261)

Brand

Leading Biology

Catalog Number

APR05870G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BAR2 Antibody (S261).

Molecular Weight

46459 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein Note=Colocalizes with VHL at the cell membrane

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

236-264 aa

Target

This BAR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-264 amino acids from human BAR2.

Isotype

Rabbit Ig

Symbol

ADRB2R, B2AR

GeneID

UniProt ID

Function

Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.

Summary

Beta-2-adrenergic receptor is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Images

Western blot analysis of anti-BAR2 Antibody (S261) (Cat.APR05870G) in mouse kidney lysates (35ug/lane). BAR2 (arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with BAR2 Antibody (S261) (Cat.APR05870G), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specification

Quantity

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