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SCDGFB Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR05726G 100 μl / $495

SCDGFB Antibody (Center)

Brand

Leading Biology

Catalog Number

APR05726G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SCDGFB Antibody (Center).

Molecular Weight

42809 Da

Cellular Localization

Antigen Cellular Localization: Secreted. Note=Released by platelets upon wounding.

Host

Rabbit

Species Reactivity

Human

Immunogen

313-341 aa

Target

This SCDGFB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-341 amino acids from the Central region of rat SCDGFB.

Isotype

Rabbit Ig

Symbol

Iegf, Scdgfb

GeneID

UniProt ID

Function

Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Plays an important role in wound healing. Induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis (By similarity). May play an important role in control of lens epithelial cell proliferation. Can initiate events that lead to a mesangial proliferative glomerulonephritis, including influx of monocytes and macrophages and production of extracellular matrix.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

IHC-P, WB, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Images

Western blot analysis of lysate from mouse liver tissue lysate, using SCDGFB Antibody (Center)(APR05726G). AP6263A was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 35ug.

Western blot analysis of lysate from rat kidney tissue lysate, using SCDGFB Antibody (Center)(APR05726G). AP6263A was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug.

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Specification

Quantity

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