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MAGEA4 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR05703G 100 μl / $495

MAGEA4 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR05703G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MAGEA4 Antibody (N-term).

Molecular Weight

34899 Da

Host

Rabbit

Species Reactivity

Human

Immunogen

9-38 aa

Target

This MAGEA4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-38 amino acids from the N-terminal region of human MAGEA4.

Isotype

Rabbit Ig

Symbol

MAGE4

GeneID

UniProt ID

Function

Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.

Summary

MAGEA4 is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in somehereditary disorders, such as dyskeratosis congenita.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:50~100

Images

The anti-MAGE-A4 Pab (Cat. APR05703G) is used in Western blot to detect MAGE-A4 in A375 cell lysate.

Immunostaining of paraformldehyde-fixed and paraffin-embedded human breast carcinoma with MAGE-A4 antibody APR05703G (1:50 dilution), followed by reacting with biotin-conjugated secondary antibody, ABC solution and developing with DAB. Cancerous cells show nuclear staining of MAGE-A4. Magnification: 40X. Data courtesy of Dr. Mi Hou, Karolinska?Institutet and University Hospital, Sweden.

Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with MAGEA4 antibody (N-term) (Cat.APR05703G), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specification

Quantity

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