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MAGEA12 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR05701G 100 μl / $495

MAGEA12 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR05701G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MAGEA12 Antibody (N-term).

Molecular Weight

34836 Da

Host

Rabbit

Species Reactivity

Human

Immunogen

81-108 aa

Target

This MAGEA12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-108 amino acids from the N-terminal region of human MAGEA12.

Isotype

Rabbit Ig

Symbol

MAGE12

GeneID

UniProt ID

Function

Not known, though may play a role tumor transformation or progression. In vitro promotes cell viability in melanoma cell lines.

Summary

MAGEA12 is a member of the melanoma antigen gene (MAGE) family. The proteins of this family are tumor-specific antigens that can be recognized by autologous cytolytic T lymphocytes. This gene is expressed in various tumors and tumor cell lines from different tissue origins, but not detected in normal tissues, except testis. The function of this gene is unknown. This and other MAGE genes form a gene cluster at chromosome Xq28 region.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Images

MAGEA12 Antibody (S96) (Cat. APR05701G) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the MAGEA12 antibody detected the MAGEA12 protein (arrow).

MAGEA12 antibody (N-term) (Cat. APR05701G)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MAGEA12 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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