> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > FKBP8 Antibody (Center)Brand |
Leading Biology | Catalog Number |
APR05693G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FKBP8 Antibody (Center).
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Molecular Weight |
44562 Da
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Cellular Localization |
Antigen Cellular Localization:
Isoform 1: Mitochondrion membrane; Single- pass membrane protein; Cytoplasmic side
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
199-226 aa
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Target |
This FKBP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 199-226 amino acids from the Central region of human FKBP8.
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Isotype |
Rabbit Ig
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Symbol |
FKBP38
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GeneID |
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UniProt ID |
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Function |
Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
FKBP8 Antibody (Center) (Cat. APR05693G) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the FKBP8 antibody detected the FKBP8 protein (arrow).
With HepG2 cell line lysate, the resolved proteins were electrophoretically transferred to PVDF membrane and incubated sequentially with primary antibody FKBP38 ( abgent, Cat. AP5990C, 1:1000, 4°C,overnight ) and horseradish peroxidase–conjugated second antibody. After washing, the bound antibody complex was detected using an ECL chemiluminescence reagentand XAR film (Kodak). |
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Specification |
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Quantity |
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Tel: 1-661-524(LBI)-0262
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