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TANK Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR05685G 100 μl / $495

TANK Antibody (Center)

Brand

Leading Biology

Catalog Number

APR05685G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TANK Antibody (Center).

Molecular Weight

47816 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm.

Host

Rabbit

Species Reactivity

Human

Immunogen

88-114 aa

Target

This TANK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 88-114 amino acids from the Central region of human TANK.

Isotype

Rabbit Ig

Symbol

ITRAF, TRAF2

GeneID

UniProt ID

Function

Adapter protein involved in I-kappa-B-kinase (IKK) regulation which constitutively binds TBK1 and IKBKE playing a role in antiviral innate immunity. Acts as a regulator of TRAF function by maintaining them in a latent state. Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation. May control negatively TRAF2-mediated NF-kappa-B activation signaled by CD40, TNFR1 and TNFR2.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, FC, E

Dilution

WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50

Images

TANK Antibody (Center) (Cat. APR05685G) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the TANK antibody detected the TANK protein (arrow).

TANK Antibody (Center) (Cat. APR05685G) immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TANK Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

TANK Antibody (Center) (Cat. APR05685G) flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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