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UBXN6 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR05477G 100 μl / $495

UBXN6 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR05477G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality UBXN6 Antibody (C-term).

Molecular Weight

49754 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Localizes at the centrosome both in interphase and during mitosis

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

281-309 aa

Target

This UBXN6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-309 amino acids from the C-terminal region of human UBXN6.

Isotype

Rabbit Ig

Symbol

UBXD1, UBXDC2

GeneID

UniProt ID

Function

Acts in a complex with VCP and cooperates with USP7 in promoting MDM2 deubiquitination and stabilization. MDM2 stabilization leads to MDM2-dependent TP53 degradation.

Summary

UBXN6 acts in a complex with VCP and cooperates with USP7 in promoting MDM2 deubiquitination and stabilization. UBXN6 is MDM2 stabilization leads to MDM2-dependent TP53 degradation.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:50~100

Images

Western blot analysis of UBXN6 Antibody (C-term) (Cat. APR05477G) in mouse kidney tissue lysates (35ug/lane).UBXN6 (arrow) was detected using the purified Pab.

UBXN6 Antibody (C-term) (Cat. APR05477G) IHC analysis in formalin fixed and paraffin embedded mouse testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the UBXN6 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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