> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > p130 Cas Antibody (Ab-410)Brand |
Leading Biology | Catalog Number |
APR05370G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality p130 Cas Antibody (Ab-410) .
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Molecular Weight |
93 KDa
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Cellular Localization |
Antigen Cellular Localization:
Cell junction, focal adhesion. Cytoplasm. Note=Unphosphorylated form localizes in the cytoplasm and can move to the membrane upon tyrosine phosphorylation.
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Host |
Rabbit
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Species Reactivity |
Human, Mouse, Rat
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Immunogen |
400-430 aa
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Symbol |
CAS, CASS1, CRKAS
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GeneID |
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UniProt ID |
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Function |
Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.
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Summary |
Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC
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Dilution |
WB~~ 1:1000
IHC~~1:50-1:100
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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