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IFM2 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR05352G 100 μl / $495

IFM2 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR05352G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IFM2 Antibody (N-term).

Molecular Weight

14632 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single-pass membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

1-30 aa

Target

This IFM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human IFM2.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against multiple viruses, including influenza A virus, SARS coronavirus (SARS-CoV), Marburg virus (MARV), Ebola virus (EBOV), Dengue virus (DNV), West Nile virus (WNV), human immunodeficiency virus type 1 (HIV-1) and vesicular stomatitis virus (VSV). Can inhibit: influenza virus hemagglutinin protein-mediated viral entry, MARV and EBOV GP1,2-mediated viral entry, SARS-CoV S protein-mediated viral entry and VSV G protein- mediated viral entry. Induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:50~100

Images

Western blot analysis of IFM2 Antibody (N-term) (Cat. APR05352G) in NCI-H460 cell line lysates (35ug/lane). IFM2 (arrow) was detected using the purified Pab.

IFM2 Antibody (N-term) (Cat. APR05352G) IHC analysis in formalin fixed and paraffin embedded lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the IFM2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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