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Phospho-mouse BAD(S96) Antibody

Catalog # Availability Size / Price Inquiry
APR05325G 100 μl / $495

Phospho-mouse BAD(S96) Antibody

Brand

Leading Biology

Catalog Number

APR05325G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-mouse BAD(S96) Antibody.

Molecular Weight

22080 Da

Cellular Localization

Antigen Cellular Localization: Mitochondrion outer membrane. Cytoplasm. Note=Upon phosphorylation, locates to the cytoplasm

Host

Rabbit

Species Reactivity

Mouse

Target

This mouse BAD Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S96 of mouse BAD.

Isotype

Rabbit Ig

Symbol

Bbc6

GeneID

UniProt ID

Function

Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.

Summary

BAD promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

DB, E

Dilution

DB~~1:500

Images

Dot blot analysis of mouse BAD Antibody (Phospho S96) Phospho-specific Pab (Cat. APR05325G) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.

Specification

Quantity

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