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Phospho-Gab1(Y659) Antibody

Catalog # Availability Size / Price Inquiry
APR05163G 100 μl / $495

Phospho-Gab1(Y659) Antibody

Brand

Leading Biology

Catalog Number

APR05163G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-Gab1(Y659) Antibody.

Molecular Weight

76616 Da

Host

Rabbit

Species Reactivity

Human

Target

This Gab1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y659 of human Gab1.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR).

Summary

Gab1 is a member of the IRS1-like multisubstrate docking protein family. This protein is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

DB, E

Dilution

DB~~1:500

Images

Dot blot analysis of Phospho-Gab1-Y659 polyclonal antibody (Cat. APR05163G) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentration were 0.5ug per ml.

Specification

Quantity

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