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OPRS1 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR05068G 100 μl / $495

OPRS1 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR05068G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality OPRS1 Antibody (Center).

Molecular Weight

25128 Da

Cellular Localization

Antigen Cellular Localization: Nucleus inner membrane. Nucleus outer membrane. Endoplasmic reticulum membrane. Lipid droplet. Cell junction. Cell membrane. Cell projection, growth cone Note=Targeted to lipid droplets, cholesterol and galactosylceramide-enriched domains of the endoplasmic reticulum Enriched at cell-cell communication regions, growth cone and postsynaptic structures. Localization is modulated by ligand- binding

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

118-147 aa

Target

This OPRS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-147 amino acids from the Central region of human OPRS1.

Isotype

Rabbit Ig

Symbol

OPRS1, SRBP

GeneID

UniProt ID

Function

Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Involved in the regulation of different receptors it plays a role in BDNF signaling and EGF signaling. Also regulates ion channels like the potassium channel and could modulate neurotransmitter release. Plays a role in calcium signaling through modulation together with ANK2 of the ITP3R-dependent calcium efflux at the endoplasmic reticulum. Plays a role in several other cell functions including proliferation, survival and death. Originally identified for its ability to bind various psychoactive drugs it is involved in learning processes, memory and mood alteration.

Summary

OPRS1 is a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

Western blot analysis of OPRS1 (arrow) using rabbit polyclonal OPRS1 Antibody (Center) (Cat.APR05068G).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the OPRS1 gene (Lane 2) (Origene Technologies).

OPRS1 Antibody (Center) (Cat.APR05068G) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the OPRS1 antibody detected the OPRS1 protein (arrow).

Specification

Quantity

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