> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Deaf1 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR05054G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Deaf1 Antibody (C-term).
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Molecular Weight |
59633 Da
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Cellular Localization |
Antigen Cellular Localization:
Isoform 1: Nucleus. Cytoplasm.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
368-400 aa
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Target |
This Deaf1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 368-400 amino acids from the C-terminal region of human Deaf1.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Transcription factor that binds to sequence with multiple copies of 5'-TTC[CG]G-3' present in its own promoter and that of the HNRPA2B1 gene. Down-regulates transcription of these genes. Binds to the retinoic acid response element (RARE) 5'- AGGGTTCACCGAAAGTTCA-3'. Activates the proenkephalin gene independently of promoter binding, probably through protein- protein interaction (By similarity). Regulates epithelial cell proliferation and side-branching in the mammary gland. Required for neural tube closure and skeletal patterning. Controls the expression of peripheral tissue antigens in pancreatic lymph nodes. Isoform 1 displays greater transcriptional activity than isoform 2. Isoform 2 may inhibit transcriptional activity of isoform 1 by interacting with it and retaining it in the cytoplasm. Transcriptional activator of EIF4G3 (By similarity). May also involved in behavior (PubMed:24726472).
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Summary |
Drosophila Deformed epidermal autoregulatory factor 1 (DEAF-1) is a DNA-binding protein that interacts with regulatory sequences first described in the Deformed epidermal autoregulatory element.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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