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PAPSS1 Antibody (N-term K9)

Catalog # Availability Size / Price Inquiry
APR05050G 100 μl / $495

PAPSS1 Antibody (N-term K9)

Brand

Leading Biology

Catalog Number

APR05050G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PAPSS1 Antibody (N-term K9).

Molecular Weight

70833 Da

Host

Rabbit

Species Reactivity

Human

Immunogen

1-30 aa

Target

This PAPSS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PAPSS1.

Isotype

Rabbit Ig

Symbol

ATPSK1, PAPSS

GeneID

UniProt ID

Function

Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate- activation pathway. Also involved in the biosynthesis of sulfated L-selectin ligands in endothelial cells.

Summary

Three-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS) is the sulfate donor cosubstrate for all sulfotransferase (SULT) enzymes. SULTs catalyze the sulfate conjugation of many endogenous and exogenous compounds, including drugs and other xenobiotics. In humans, PAPS is synthesized from adenosine 5-prime triphosphate (ATP) and inorganic sulfate by 2 isoforms, PAPSS1 and PAPSS2.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

Western blot analysis of PAPSS1 antibody (N-term K9) (Cat. APR05050G) in CEM cell line lysates (35ug/lane). PAPSS1 (arrow) was detected using the purified Pab.

Specification

Quantity

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