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NACA2 Antibody (N-Term)

Catalog # Availability Size / Price Inquiry
APR04901G 100 μl / $495

NACA2 Antibody (N-Term)

Brand

Leading Biology

Catalog Number

APR04901G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NACA2 Antibody (N-Term).

Molecular Weight

23223 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Nucleus

Host

Rabbit

Species Reactivity

Human

Target

This NACA2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 36-69 amino acids from human NACA2.

Isotype

Rabbit Ig

Symbol

NACAL

GeneID

UniProt ID

Function

Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites) (By similarity).

Summary

Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites) (By similarity).

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:2000

Images

Anti-NACA2 Antibody (N-Term) at 1:2000 dilution + human skeletal muscle lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 23 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Specification

Quantity

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