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Mouse Myocd Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR04747G 100 μl / $495

Mouse Myocd Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR04747G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Mouse Myocd Antibody (C-term).

Molecular Weight

101400 Da

Cellular Localization

Antigen Cellular Localization: Nucleus speckle Note=Nuclear, with a punctate intranuclear pattern with exclusion from nuclei

Host

Rabbit

Species Reactivity

Mouse

Target

This Mouse Myocd antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 743-777 amino acids from the C-terminal region of Mouse Myocd.

Isotype

Rabbit Ig

Symbol

Bsac2, Mycd, Srfcp

GeneID

UniProt ID

Function

Smooth muscle cells (SM) and cardiac muscle cells- specific transcriptional factor which uses the canonical single or multiple CArG boxes DNA sequence. Acts as a cofactor of serum response factor (SRF) with the potential to modulate SRF-target genes. Plays a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage (myogenesis). Isoform 1 mediates the cardiac transcription factor MEF2C-dependent transcription. Isoform 1 and isoform 3 are more active than isoform 2 and isoform 4 in stimulating cardiac muscle promoters.

Summary

Smooth muscle cells (SM) and cardiac muscle cells- specific transcriptional factor which uses the canonical single or multiple CArG boxes DNA sequence. Acts as a cofactor of serum response factor (SRF) with the potential to modulate SRF-target genes. Plays a crucial role in cardiogenesis and differentiation of the smooth muscle cell lineage (myogenesis). Isoform 1 mediates the cardiac transcription factor MEF2C-dependent transcription. Isoform 1 and isoform 3 are more active than isoform 2 and isoform 4 in stimulating cardiac muscle promoters.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

Anti-Myocd Antibody (Cterm) at 1:2000 dilution + C2C12 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 101 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Western blot analysis of lysate from mouse C2C12 cell line, using Myocd Antibody (C-term)(APR04747G). APR04747G was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.

Specification

Quantity

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