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FOXN4 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR04726G 100 μl / $495

FOXN4 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR04726G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FOXN4 Antibody (Center).

Molecular Weight

55215 Da

Cellular Localization

Antigen Cellular Localization: Nucleus {ECO:0000255|PROSITE- ProRule:PRU00089}

Host

Rabbit

Species Reactivity

Human

Target

This FOXN4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 314-349 amino acids from the Central region of human FOXN4.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Transcription factor essential for neural and some non- neural tissues development, such as retina and lung respectively. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, is required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates through activating DLL4- NOTCH signaling. Also acts synergistically with ASCL1/MASH1 to activate DLL4-NOTCH signaling and drive commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the atrioventricular canal and is indirectly required for patterning the distal airway during lung development (By similarity).

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

Western blot analysis of lysate from human brain tissue lysate, using FOXN4 Antibody (Center)(APR04726G). APR04726G was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.

Specification

Quantity

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