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SPNXB Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR04536G 100 μl / $495

SPNXB Antibody (Center)

Brand

Leading Biology

Catalog Number

APR04536G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SPNXB Antibody (Center).

Molecular Weight

11826 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Nucleus. Note=Associated with nuclear craters

Host

Rabbit

Species Reactivity

Human

Immunogen

17-47 aa

Target

This SPNXB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-47 amino acids from the Central region of human SPNXB.

Isotype

Rabbit Ig

Symbol

SPANXB

GeneID

UniProt ID

Summary

Temporally regulated transcription and translation ofseveral testis-specific genes is required to initiate the series ofmolecular and morphological changes in the male germ cell lineagenecessary for the formation of mature spermatozoa. This gene is amember of the SPANX family of cancer/testis-associated genes, whichare located in a cluster on chromosome X. The SPANX genes encodedifferentially expressed testis-specific proteins that localize tovarious subcellular compartments. This particular gene maps tochromosome X in a head-to-tail orientation with SPANX family memberB1 and appears to be a duplication of that locus. The SPANXB genesare unique members of this gene family, since they contain anadditional 18 nt in their coding region compared to the majority offamily members. Although the protein encoded by this gene containsconsensus nuclear localization signals, the major site forsubcellular localization of expressed protein is in the cytoplasmicdroplets of ejaculated spermatozoa. This protein provides abiochemical marker for studying the unique structures inspermatazoa, while attempting to further define its role inspermatogenesis.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

SPNXB Antibody (Center) (Cat. APR04536G) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the SPNXB antibody detected the SPNXB protein (arrow).

Specification

Quantity

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