> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > RGS2 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR04526G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RGS2 Antibody (N-term).
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Molecular Weight |
24382 Da
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Cellular Localization |
Antigen Cellular Localization:
Isoform 1: Cell membrane. Cytoplasm. Nucleus, nucleolus Isoform 3: Cell membrane. Cytoplasm. Nucleus, nucleolus
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
4-32 aa
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Target |
This RGS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 4-32 amino acids from the N-terminal region of human RGS2.
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Isotype |
Rabbit Ig
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Symbol |
G0S8
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GeneID |
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UniProt ID |
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Function |
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. May play a role in leukemogenesis. Plays a role in negative feedback control pathway for adenylyl cyclase signaling. Binds EIF2B5 and blocks its activity, thereby inhibiting the translation of mRNA into protein.
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Summary |
Regulator of G protein signaling (RGS) family members areregulatory molecules that act as GTPase activating proteins (GAPs)for G alpha subunits of heterotrimeric G proteins. RGS proteins areable to deactivate G protein subunits of the Gi alpha, Go alpha andGq alpha subtypes. They drive G proteins into their inactiveGDP-bound forms. Regulator of G protein signaling 2 belongs to thisfamily. The protein acts as a mediator of myeloid differentiationand may play a role in leukemogenesis.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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