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FCER1G Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR04490G 100 μl / $495

FCER1G Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR04490G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FCER1G Antibody (C-term).

Molecular Weight

9667 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein

Host

Rabbit

Species Reactivity

Human

Immunogen

60-86 aa

Target

This FCER1G antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-86 amino acids from the C-terminal region of human FCER1G.

Isotype

Rabbit IgG

GeneID

UniProt ID

Function

Associates with a variety of FcR alpha chains to form a functional signaling complex. Regulates several aspects of the immune response. The gamma subunit has a critical role in allowing the IgE Fc receptor to reach the cell surface. Also involved in collagen-mediated platelet activation and in neutrophil activation mediated by integrin.

Summary

The high affinity IgE receptor is a key molecule involvedin allergic reactions. It is a tetramer composed of 1 alpha, 1beta, and 2 gamma chains. The gamma chains are also subunits ofother Fc receptors.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

IHC-P~~1:25 WB~~1:1000

Images

Immunohistochemical analysis of paraffin-embedded H. spleen section using FCER1G Antibody (C-term)( APR04490G). APR04490G was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.

Western blot analysis of lysate from human spleen tissue lysate, using FCER1G Antibody (C-term)(Cat. APR04490G). APR04490G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.

Western blot analysis of lysate from human spleen tissue lysate, using FCER1G Antibody (C-term)(Cat. APR04490G). APR04490G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.

Specification

Quantity

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