> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > MMP26 Antibody (Center)Brand |
Leading Biology | Catalog Number |
APR04485G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MMP26 Antibody (Center).
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Molecular Weight |
29708 Da
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Cellular Localization |
Antigen Cellular Localization:
Secreted, extracellular space, extracellular matrix
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
96-125 aa
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Target |
This MMP26 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-125 amino acids from the Central region of human MMP26.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
May hydrolyze collagen type IV, fibronectin, fibrinogen, beta-casein, type I gelatin and alpha-1 proteinase inhibitor. Is also able to activate progelatinase B.
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Summary |
Proteins of the matrix metalloproteinase (MMP) family areinvolved in the breakdown of extracellular matrix in normalphysiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in diseaseprocesses, such as arthritis and metastasis. Most MMP's aresecreted as inactive proproteins which are activated when cleavedby extracellular proteinases. The encoded protein degrades type IVcollagen, fibronectin, fibrinogen, casein, vitronectin, alpha1-antitrypsin, alpha 2-macroglobulin, and insulin-like growthfactor-binding protein 1, and activates MMP9 by cleavage. Theprotein differs from most MMP family members in that it lacks aconserved C-terminal protein domain.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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