> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > PPP2R1A Antibody(C-term)Brand |
Leading Biology | Catalog Number |
APR04462G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PPP2R1A Antibody(C-term).
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Molecular Weight |
65309 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Chromosome, centromere. Note=Centromeric localization requires the presence of BUB1
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
454-481 aa
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Target |
This PPP2R1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 454-481 amino acids from the C-terminal region of human PPP2R1A.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Required for proper chromosome segregation and for centromeric localization of SGOL1 in mitosis.
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Summary |
This gene encodes a constant regulatory subunit of proteinphosphatase 2. Protein phosphatase 2 is one of the four majorSer/Thr phosphatases, and it is implicated in the negative controlof cell growth and division. It consists of a common heteromericcore enzyme, which is composed of a catalytic subunit and aconstant regulatory subunit, that associates with a variety ofregulatory subunits. The constant regulatory subunit A serves as ascaffolding molecule to coordinate the assembly of the catalyticsubunit and a variable regulatory B subunit. This gene encodes analpha isoform of the constant regulatory subunit A. Alternativelyspliced transcript variants have been described. [provided byRefSeq].
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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