> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > DPEP1 Antibody(N-term)Brand |
Leading Biology | Catalog Number |
APR04454G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DPEP1 Antibody(N-term).
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Molecular Weight |
45674 Da
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Cellular Localization |
Antigen Cellular Localization:
Apical cell membrane; Lipid-anchor, GPI- anchor. Cell projection, microvillus membrane; Lipid-anchor, GPI- anchor. Note=Brush border membrane
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
1-30 aa
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Target |
This DPEP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DPEP1.
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Isotype |
Rabbit Ig
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Symbol |
MDP, RDP
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GeneID |
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UniProt ID |
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Function |
Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity.
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Summary |
DPEP1 (EC 3.4.13.11) is a kidney membrane enzyme thathydrolyzes a variety of dipeptides and is implicated in renalmetabolism of glutathione and its conjugates, e.g., leukotriene D4(Kozak and Tate, 1982 [PubMed 6122685]). DPEP1 is responsible forhydrolysis of the beta-lactam ring of antibiotics, such as penemand carbapenem (Campbell et al., 1984 [PubMed 6334084]). Earlier,beta-lactamase enzymes were thought to occur only in bacteria,where their probable function was in protecting the organismsagainst the action of beta-lactam antibiotics. These antibioticsexhibit selective toxicity against bacteria but virtual inertnessagainst many eukaryotic cells (Adachi et al., 1990 [PubMed2303490]).
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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