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OPCML Antibody(Center)

Catalog # Availability Size / Price Inquiry
APR04449G 100 μl / $495

OPCML Antibody(Center)

Brand

Leading Biology

Catalog Number

APR04449G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality OPCML Antibody(Center).

Molecular Weight

38008 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Lipid-anchor, GPI-anchor

Host

Rabbit

Species Reactivity

Human

Immunogen

172-200 aa

Target

This OPCML antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-200 amino acids from the Central region of human OPCML.

Isotype

Rabbit Ig

Symbol

IGLON1, OBCAM

GeneID

UniProt ID

Function

Binds opioids in the presence of acidic lipids; probably involved in cell contact.

Summary

This gene encodes a member of the IgLON subfamily in theimmunoglobulin protein superfamily. The encoded protein islocalized in the plasma membrane and may have an accessory role inopioid receptor function. This gene has an ortholog in rat andbovine. The opioid binding-cell adhesion molecule encoded by therat gene binds opioid alkaloids in the presence of acidic lipids,exhibits selectivity for mu ligands and acts as a GPI-anchoredprotein. Since the encoded protein is highly conserved in speciesduring evolution, it may have a fundamental role in mammaliansystems. Two transcript variants encoding different isoforms havebeen found for this gene.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

OPCML Antibody (Center) (Cat. APR04449G) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the OPCML antibody detected the OPCML protein (arrow).

Specification

Quantity

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