> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > CCNDBP1 Antibody(N-term)Brand |
Leading Biology | Catalog Number |
APR04428G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CCNDBP1 Antibody(N-term).
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Molecular Weight |
40262 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm. Nucleus.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
21-49 aa
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Target |
This CCNDBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-49 amino acids from the N-terminal region of human CCNDBP1.
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Isotype |
Rabbit Ig
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Symbol |
DIP1, GCIP, HHM
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GeneID |
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UniProt ID |
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Function |
May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F- dependent transcription.
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Summary |
This gene was identified by the interaction of its geneproduct with Grap2, a leukocyte-specific adaptor protein importantfor immune cell signaling. The protein encoded by this gene wasshown to interact with cyclin D. Transfection of this gene in cellswas reported to reduce the phosphorylation of Rb gene product bycyclin D-dependent protein kinase, and inhibit E2F1-mediatedtranscription activity. This protein was also found to interactwith helix-loop-helix protein E12 and is thought to be a negativeregulator of liver-specific gene expression. Several alternativelyspliced variants have been found for this gene. [provided byRefSeq].
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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