> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > Mouse BAD Antibody (Center S134)Brand |
Leading Biology | Catalog Number |
APR04409G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Mouse BAD Antibody (Center S134).
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Molecular Weight |
22080 Da
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Cellular Localization |
Antigen Cellular Localization:
Mitochondrion outer membrane. Cytoplasm. Note=Upon phosphorylation, locates to the cytoplasm
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Host |
Rabbit
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Species Reactivity |
Mouse
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Immunogen |
112-141 aa
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Target |
This Mouse BAD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112-141 amino acids from the Central region of mouse BAD.
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Isotype |
Rabbit Ig
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Symbol |
Bbc6
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GeneID |
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UniProt ID |
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Function |
Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
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Summary |
BAD promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2. Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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