> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > TIGAR Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR04405G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TIGAR Antibody (N-term).
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Molecular Weight |
30063 Da
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Host |
Rabbit
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Species Reactivity |
Mouse
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Immunogen |
1-30 aa
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Target |
This TIGAR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TIGAR.
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Isotype |
Rabbit Ig
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Symbol |
C12orf5
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GeneID |
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UniProt ID |
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Function |
Fructose-bisphosphatase hydrolyzing fructose-2,6- bisphosphate as well as fructose-1,6-bisphosphate. Inhibits glycolysis by reducing cellular levels of fructose-2,6- bisphosphate. May protect cells against reactive oxygen species and against apoptosis induced by tp53.
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Summary |
This gene is regulated as part of the p53 tumor suppressorpathway and encodes a protein with sequence similarity to thebisphosphate domain of the glycolytic enzyme that degradesfructose-2,6-bisphosphate. The protein functions by blockingglycolysis and directing the pathway into the pentose phosphateshunt. Expression of this protein also protects cells from DNAdamaging reactive oxygen species and provides some protection fromDNA damage-induced apoptosis. The 12p13.32 region that includesthis gene is paralogous to the 11q13.3 region. [provided byRefSeq].
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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