> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > RASA3 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR04386G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RASA3 Antibody (C-term).
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Molecular Weight |
95699 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
594-623 aa
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Target |
This RASA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 594-623 amino acids from the C-terminal region of human RASA3.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4) with high affinity. Might be a specific IP4 receptor.
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Summary |
The protein encoded by this gene is member of the GAP1family of GTPase-activating proteins. The gene product stimulatesthe GTPase activity of normal RAS p21 but not its oncogeniccounterpart. Acting as a suppressor of RAS function, the proteinenhances the weak intrinsic GTPase activity of RAS proteinsresulting in the inactive GDP-bound form of RAS, thereby allowingcontrol of cellular proliferation and differentiation. This familymember is an inositol 1,3,4,5-tetrakisphosphate-binding protein,like the closely related RAS p21 protein activator 2. The twofamily members have distinct pleckstrin-homology domains, with thisparticular member having a domain consistent with its localizationto the plasma membrane.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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