> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > ANAPC4 Antibody (Center)Brand |
Leading Biology | Catalog Number |
APR04255G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ANAPC4 Antibody (Center).
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Molecular Weight |
92116 Da
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
638-664 aa
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Target |
This ANAPC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 638-664 amino acids from the Central region of human ANAPC4.
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Isotype |
Rabbit Ig
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Symbol |
APC4
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GeneID |
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UniProt ID |
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Function |
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
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Summary |
A large protein complex, termed the anaphase-promotingcomplex (APC), or the cyclosome, promotes metaphase-anaphasetransition by ubiquitinating its specific substrates such asmitotic cyclins and anaphase inhibitor, which are subsequentlydegraded by the 26S proteasome. Biochemical studies have shown thatthe vertebrate APC contains eight subunits. The composition of theAPC is highly conserved in organisms from yeast to humans. Theexact function of this gene product is not known. [provided byRefSeq].
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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