> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > MYH7 Antibody (N-term)Brand |
Leading Biology | Catalog Number |
APR04234G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MYH7 Antibody (N-term).
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Molecular Weight |
223097 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm, myofibril. Note=Thick filaments of the myofibrils
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Host |
Rabbit
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Species Reactivity |
Human, Mouse
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Immunogen |
185-211 aa
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Target |
This MYH7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-211 amino acids from the N-terminal region of human MYH7.
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Isotype |
Rabbit Ig
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Symbol |
MYHCB
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GeneID |
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UniProt ID |
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Function |
Muscle contraction.
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Summary |
Muscle myosin is a hexameric protein containing 2 heavychain subunits, 2 alkali light chain subunits, and 2 regulatorylight chain subunits. This gene encodes the beta (or slow) heavychain subunit of cardiac myosin. It is expressed predominantly innormal human ventricle. It is also expressed in skeletal muscletissues rich in slow-twitch type I muscle fibers. Changes in therelative abundance of this protein and the alpha (or fast) heavysubunit of cardiac myosin correlate with the contractile velocityof cardiac muscle. Its expression is also altered during thyroidhormone depletion and hemodynamic overloading. Mutations in thisgene are associated with familial hypertrophic cardiomyopathy,myosin storage myopathy, dilated cardiomyopathy, and Laingearly-onset distal myopathy.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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