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HECTD3 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR04212G 100 μl / $495

HECTD3 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR04212G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HECTD3 Antibody (C-term).

Molecular Weight

97113 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm, perinuclear region.

Host

Rabbit

Species Reactivity

Human

Immunogen

740-769 aa

Target

This HECTD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 740-769 amino acids from the C-terminal region of human HECTD3.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

E3 ubiquitin ligases accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of TRIOBP and its subsequent proteasomal degradation, thus faciliting cell cycle progression by regulating the turn-over of TRIOBP. Mediates also ubiquitination of STX8 (By similarity).

Summary

E3 ubiquitin ligases accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of TRIOBP and its subsequent proteasomal degradation, thus faciliting cell cycle progression by regulating the turn-over of TRIOBP. Mediates also ubiquitination of STX8 (By similarity).

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

HECTD3 Antibody (C-term) (Cat. APR04212G) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the HECTD3 antibody detected the HECTD3 protein (arrow).

Specification

Quantity

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