> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > MYOT Antibody (Center)Brand |
Leading Biology | Catalog Number |
APR04193G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MYOT Antibody (Center).
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Molecular Weight |
55395 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane, sarcolemma. Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line Note=Sarcomeric, also localized to the sarcolemma. Colocalizes with MYOZ1 at the Z-lines in skeletal muscle
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
127-155 aa
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Target |
This MYOT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-155 amino acids from the Central region of human MYOT.
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Isotype |
Rabbit Ig
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Symbol |
TTID
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GeneID |
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UniProt ID |
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Function |
Component of a complex of multiple actin cross-linking proteins. Involved in the control of myofibril assembly and stability at the Z lines in muscle cells.
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Summary |
This gene encodes a cystoskeletal protein which plays asignificant role in the stability of thin filaments during musclecontraction. This protein binds F-actin, crosslinks actinfilaments, and prevents latrunculin A-induced filament disassembly.Mutations in this gene have been associated with limb-girdlemuscular dystrophy and myofibrillar myopathies. Severalalternatively spliced transcript variants of this gene have beendescribed, but the full-length nature of some of these variants hasnot been determined.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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