> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > TRAFD1 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR04190G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TRAFD1 Antibody (C-term).
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Molecular Weight |
64841 Da
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
542-569 aa
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Target |
This TRAFD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 542-569 amino acids from the C-terminal region of human TRAFD1.
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Isotype |
Rabbit Ig
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Symbol |
FLN29
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GeneID |
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UniProt ID |
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Function |
Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3 (By similarity).
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Summary |
The innate immune system confers host defense againstviral and microbial infection, and TRAFD1 is a negative feedbackregulator that controls excessive immune responses (Sanada et al.,2008 [PubMed 18849341]).
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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