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F9 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR04159G 100 μl / $495

F9 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR04159G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality F9 Antibody (Center).

Molecular Weight

51778 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human

Immunogen

266-295 aa

Target

This F9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 266-295 amino acids from the Central region of human F9.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.

Summary

This gene encodes vitamin K-dependent coagulation factorIX that circulates in the blood as an inactive zymogen. This factoris converted to an active form by factor XIa, which excises theactivation peptide and thus generates a heavy chain and a lightchain held together by one or more disulfide bonds. The role ofthis activated factor IX in the blood coagulation cascade is toactivate factor X to its active form through interactions with Ca+2ions, membrane phospholipids, and factor VIII. Alterations of thisgene, including point mutations, insertions and deletions, causefactor IX deficiency, which is a recessive X-linked disorder, alsocalled hemophilia B or Christmas disease.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

All lanes : Anti-F9 Antibody (Center) at 1:2000 dilution Lane 1: 293T/17 whole cell lysate Lane 2: A431 whole cell lysate Lane 3: HepG2 whole cell lysate Lane 4: K562 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 51 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

F9 Antibody (Center) (Cat. APR04159G) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the F9 antibody detected the F9 protein (arrow).

Specification

Quantity

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