> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > DSC3 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR04137G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DSC3 Antibody (C-term).
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Molecular Weight |
99969 Da
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Cellular Localization |
Antigen Cellular Localization:
Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
822-850 aa
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Target |
This DSC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 822-850 amino acids from the C-terminal region of human DSC3.
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Isotype |
Rabbit Ig
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Symbol |
CDHF3, DSC4
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GeneID |
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UniProt ID |
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Function |
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.
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Summary |
The protein encoded by this gene is a calcium-dependentglycoprotein that is a member of the desmocollin subfamily of thecadherin superfamily. These desmosomal family members, along withthe desmogleins, are found primarily in epithelial cells where theyconstitute the adhesive proteins of the desmosome cell-celljunction and are required for cell adhesion and desmosomeformation. The desmosomal family members are arranged in twoclusters on chromosome 18, occupying less than 650 kb combined.Alternative splicing results in two transcript variants encodingdistinct isoforms.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
Western blot analysis of lysate from A431 cell line, using DSC3 Antibody (C-term)(Cat. APR04137G). APR04137G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane. |
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Specification |
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Quantity |
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| Select | Brand | Catalog No. | Product Name | Pack Size | Type | Field of Research | Specification | Quantity | Price(USD) | |
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| 3 | Leading Biology | APR12422G | Human H4 Histamine Receptor (extracellular) Antibody | 50 μl | Polyclonal Antibodies |
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| 4 | Leading Biology | APR03844G | UBE2W Antibody (C-term) | 100 μl | Polyclonal Antibodies |
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| 5 | Leading Biology | APR04349G | HECTD2 Antibody (N-term) | 100 μl | Polyclonal Antibodies |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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$495.00 | Add Ask |
Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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