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ASB3 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR04135G 100 μl / $495

ASB3 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR04135G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ASB3 Antibody (N-term).

Molecular Weight

57745 Da

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

15-42 aa

Target

This ASB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-42 amino acids from the N-terminal region of human ASB3.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes TNFRSF1B.

Summary

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but some of the full length sequences are not known.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

Western blot analysis of ASB3 Antibody (N-term) Pab (Cat. APR04135G) pre-incubated without(lane 1) and with(lane 2) blocking peptide in A549 cell line lysate. ASB3 Antibody (N-term) (arrow) was detected using the purified Pab.

Western blot analysis of ASB3 Antibody (N-term) Pab (Cat. APR04135G) pre-incubated without(lane 1) and with(lane 2) blocking peptide in mouse spleen tissue lysate. ASB3 Antibody (N-term) (arrow) was detected using the purified Pab.

Specification

Quantity

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