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TGFBI Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR04129G 100 μl / $495

TGFBI Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR04129G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TGFBI Antibody (N-term).

Molecular Weight

74681 Da

Cellular Localization

Antigen Cellular Localization: Secreted, extracellular space, extracellular matrix. Note=May be associated both with microfibrils and with the cell surface

Host

Rabbit

Species Reactivity

Human

Immunogen

106-135 aa

Target

This TGFBI antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-135 amino acids from the N-terminal region of human TGFBI.

Isotype

Rabbit Ig

Symbol

BIGH3

GeneID

UniProt ID

Function

Binds to type I, II, and IV collagens. This adhesion protein may play an important role in cell-collagen interactions. In cartilage, may be involved in endochondral bone formation.

Summary

This gene encodes an RGD-containing protein that binds totype I, II and IV collagens. The RGD motif is found in manyextracellular matrix proteins modulating cell adhesion and servesas a ligand recognition sequence for several integrins. Thisprotein plays a role in cell-collagen interactions and may beinvolved in endochondrial bone formation in cartilage. The proteinis induced by transforming growth factor-beta and acts to inhibitcell adhesion. Mutations in this gene are associated with multipletypes of corneal dystrophy.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, FC, E

Dilution

WB~~1:1000 FC~~1:10~50

Images

Western blot analysis of TGFBI (arrow) using rabbit polyclonal TGFBI Antibody (N-term) (Cat. APR04129G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the TGFBI gene.

TGFBI Antibody (N-term) (Cat. APR04129G) flow cytometric analysis of U251 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specification

Quantity

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