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Mouse Nlrp6 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR04126G 100 μl / $495

Mouse Nlrp6 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR04126G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Mouse Nlrp6 Antibody (Center).

Molecular Weight

97402 Da

Cellular Localization

Antigen Cellular Localization: Isoform 1: Cytoplasm. Cell membrane. Nucleus membrane

Host

Rabbit

Species Reactivity

Mouse

Immunogen

343-372 aa

Target

This Mouse Nlrp6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-372 amino acids from the Central region of mouse Nlrp6.

Isotype

Rabbit Ig

Symbol

Nalp6, Pypaf5

GeneID

UniProt ID

Function

May contribute to arginine-vasopressin (AVP)-mediated regulation of renal salt-water balance, glucose and lipid metabolism, apoptosis, and/or cell cycle. Isoform 1 binds arginine-vasopressin but not angiotensin II and acts as an arginine-vasopressin V2 receptor. Isoform 2 binds both arginine- vasopressin and angiotensin II and acts as an angiotensin II/vasopressin receptor. Plays a role in modulating inflammatory responses in the colon to allow recovery from intestinal epithelial damage and limit tumorigenic potential. Protects against the development of colitis by controlling the composition of the gut microbiota by preventing colonization of the colon by harmful, inflammation-inducing bacteria such as Prevotella species. May mediate activation of CASP1 via ASC, promote activation of NF-kappa-B and stimulate cAMP accumulation.

Summary

Nlrp6 may mediate activation of CASP1 via ASC and promote activation of NF-kappa-B (By similarity).

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:2000

Images

Anti-NLRP6 Antibody at 1:2000 dilution + mouse heart lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 97 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Specification

Quantity

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