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PLEKHF1 Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR04114G 100 μl / $495

PLEKHF1 Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR04114G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PLEKHF1 Antibody (N-term).

Molecular Weight

31195 Da

Cellular Localization

Antigen Cellular Localization: Nucleus. Cytoplasm, perinuclear region Lysosome. Note=Translocates to lysosome during apoptosis

Host

Rabbit

Species Reactivity

Human

Immunogen

51-79 aa

Target

This PLEKHF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human PLEKHF1.

Isotype

Rabbit Ig

Symbol

APPD, LAPF, ZFYVE15

GeneID

UniProt ID

Function

May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase- independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8.

Summary

PLEKHF1 may induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

Anti-PLEKHF1 Antibody (N-term) at 1:1000 dilution + human heart lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 31 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Specification

Quantity

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