> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > ACTN2 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR04045G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ACTN2 Antibody (C-term).
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Molecular Weight |
103854 Da
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Cellular Localization |
Antigen Cellular Localization:
Cytoplasm, myofibril, sarcomere, Z line Note=Colocalizes with MYOZ1 and FLNC at the Z-lines of skeletal muscle
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Host |
Rabbit
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Species Reactivity |
Mouse
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Immunogen |
751-779 aa
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Target |
This ACTN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 751-779 amino acids from the C-terminal region of human ACTN2.
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Isotype |
Rabbit Ig
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GeneID |
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UniProt ID |
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Function |
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
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Summary |
Alpha actinins belong to the spectrin gene superfamilywhich represents a diverse group of cytoskeletal proteins,including the alpha and beta spectrins and dystrophins. Alphaactinin is an actin-binding protein with multiple roles indifferent cell types. In nonmuscle cells, the cytoskeletal isoformis found along microfilament bundles and adherens-type junctions,where it is involved in binding actin to the membrane. In contrast,skeletal, cardiac, and smooth muscle isoforms are localized to theZ-disc and analogous dense bodies, where they help anchor themyofibrillar actin filaments. This gene encodes a muscle-specific,alpha actinin isoform that is expressed in both skeletal andcardiac muscles.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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