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ALPP Antibody (N-term)

Catalog # Availability Size / Price Inquiry
APR04042G 100 μl / $495

ALPP Antibody (N-term)

Brand

Leading Biology

Catalog Number

APR04042G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ALPP Antibody (N-term).

Molecular Weight

57954 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Lipid-anchor, GPI-anchor.

Host

Rabbit

Species Reactivity

Human

Immunogen

56-83 aa

Target

This ALPP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 56-83 amino acids from the N-terminal region of human ALPP.

Isotype

Rabbit Ig

Symbol

PLAP

GeneID

UniProt ID

Summary

There are at least four distinct but related alkalinephosphatases: intestinal, placental, placental-like, andliver/bone/kidney (tissue non-specific). The first three arelocated together on chromosome 2 while the tissue non-specific formis located on chromosome 1. The product of this gene is a membranebound glycosylated enzyme, also referred to as the heat stableform, that is expressed primarily in the placenta although it isclosely related to the intestinal form of the enzyme as well as tothe placental-like form. The coding sequence for this form ofalkaline phosphatase is unique in that the 3' untranslated regioncontains multiple copies of an Alu family repeat. In addition, thisgene is polymorphic and three common alleles (type 1, type 2 andtype 3) for this form of alkaline phosphatase have been wellcharacterized.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Images

ALPP Antibody (N-term) (Cat. APR04042G) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the ALPP antibody detected the ALPP protein (arrow).

Western blot analysis of ALPP (arrow) using rabbit polyclonal ALPP Antibody (N-term) (Cat. APR04042G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ALPP gene.

ALPP Antibody (N-term) (APR04042G)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ALPP Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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