> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > HYAL1 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR04036G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HYAL1 Antibody (C-term).
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Molecular Weight |
48368 Da
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Cellular Localization |
Antigen Cellular Localization:
Secreted. Lysosome
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
280-309 aa
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Target |
This HYAL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 280-309 amino acids from the C-terminal region of human HYAL1.
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Isotype |
Rabbit Ig
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Symbol |
LUCA1
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GeneID |
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UniProt ID |
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Function |
May have a role in promoting tumor progression. May block the TGFB1-enhanced cell growth.
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Summary |
This gene encodes a lysosomal hyaluronidase.Hyaluronidases intracellularly degrade hyaluronan, one of the majorglycosaminoglycans of the extracellular matrix. Hyaluronan isthought to be involved in cell proliferation, migration anddifferentiation. This enzyme is active at an acidic pH and is themajor hyaluronidase in plasma. Mutations in this gene areassociated with mucopolysaccharidosis type IX, or hyaluronidasedeficiency. The gene is one of several related genes in a region ofchromosome 3p21.3 associated with tumor suppression. Multipletranscript variants encoding different isoforms have been found forthis gene.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, IHC-P, E
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Dilution |
WB~~1:1000
IHC-P~~1:10~50
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Images |
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Specification |
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Quantity |
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Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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