> Antigen, Antibodies, ELISA, Western Blot > Primary Antibody > Polyclonal Antibodies > PCSK6 Antibody (C-term)Brand |
Leading Biology | Catalog Number |
APR04024G |
Product Type |
Polyclonal Antibodies | Field of Research |
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Product Overview |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PCSK6 Antibody (C-term).
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Molecular Weight |
106420 Da
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Cellular Localization |
Antigen Cellular Localization:
Isoform PACE4A-I: Secreted. Isoform PACE4C: Endoplasmic reticulum. Note=Not secreted, remains probably in zymogen form in endoplasmic reticulum Isoform PACE4E-I: Endomembrane system; Peripheral membrane protein. Note=Retained intracellularly probably through a hydrophobic cluster in their C-terminus Isoform PACE4B: Secreted.
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Host |
Rabbit
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Species Reactivity |
Human
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Immunogen |
659-688 aa
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Target |
This PCSK6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 659-688 amino acids from the C-terminal region of human PCSK6.
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Isotype |
Rabbit IgG
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Symbol |
PACE4
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GeneID |
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UniProt ID |
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Function |
Likely to represent an endoprotease activity within the constitutive secretory pathway, with unique restricted distribution in both neuroendocrine and non-neuroendocrine tissues and capable of cleavage at the RX(K/R)R consensus motif.
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Summary |
The protein encoded by this gene belongs to thesubtilisin-like proprotein convertase family. The members of thisfamily are proprotein convertases that process latent precursorproteins into their biologically active products. This encodedprotein is a calcium-dependent serine endoprotease that can cleaveprecursor protein at their paired basic amino acid processingsites. Some of its substrates are - transforming growth factor betarelated proteins, proalbumin, and von Willebrand factor. This geneis thought to play a role in tumor progression. Alternativelyspliced transcript variants encoding different isoforms have beenidentified.
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Storage & Stability |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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Applications |
WB, E
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Dilution |
WB~~1:1000
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Images |
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Specification |
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Quantity |
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| 4 | Leading Biology | APR03844G | UBE2W Antibody (C-term) | 100 μl | Polyclonal Antibodies |
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| 5 | Leading Biology | APR04349G | HECTD2 Antibody (N-term) | 100 μl | Polyclonal Antibodies |
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| 6 | Leading Biology | APR03502G | IGHG1 Antibody (Center) | 100 μl | Polyclonal Antibodies |
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$495.00 | Add Ask |
Leading Biology Inc.
2600 Hilltop DR, Building G, B Suite C138
Richmond, CA, 94806
Tel: 1-661-524(LBI)-0262
Email: info@leadingbiology.com
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