• Account
  • Account
    Inquiries
    0

    Inquired items

    0 items total Subtotal:$ 0
  • 会员中心
    Cart

    Added items

    0items total Subtotal:$ 0

All Departments

GPC3 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR04020G 100 μl / $495

GPC3 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR04020G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GPC3 Antibody (C-term).

Molecular Weight

65563 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side

Host

Rabbit

Species Reactivity

Human

Immunogen

465-494 aa

Target

This GPC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 465-494 amino acids from the C-terminal region of human GPC3.

Isotype

Rabbit Ig

Symbol

OCI5

GeneID

UniProt ID

Function

Cell surface proteoglycan that bears heparan sulfate. Inhibits the dipeptidyl peptidase activity of DPP4. May be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs. May play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. May regulate growth and tumor predisposition.

Summary

Cell surface heparan sulfate proteoglycans are composed ofa membrane-associated protein core substituted with a variablenumber of heparan sulfate chains. Members of the glypican-relatedintegral membrane proteoglycan family (GRIPS) contain a coreprotein anchored to the cytoplasmic membrane via a glycosylphosphatidylinositol linkage. These proteins may play a role in thecontrol of cell division and growth regulation. The protein encodedby this gene can bind to and inhibit the dipeptidyl peptidaseactivity of CD26, and it can induce apoptosis in certain celltypes. Deletion mutations in this gene are associated withSimpson-Golabi-Behmel syndrome, also known as Simpson dysmorphiasyndrome. Alternative splicing results in multiple transcriptvariants.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

GPC3 Antibody (C-term) (Cat. APR04020G) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the GPC3 antibody detected the GPC3 protein (arrow).

Specification

Quantity

Related Products

Select Brand Catalog No. Product Name Pack Size Type Field of Research Specification Quantity Price(USD)
1 Leading Biology APR03440G ITGA11 Antibody (N-term) 100 μl Polyclonal Antibodies
$495.00 Add Ask
2 Leading Biology APR04537G CMIP Antibody (C-term) 100 μl Polyclonal Antibodies
$495.00 Add Ask
3 Leading Biology APR12422G Human H4 Histamine Receptor (extracellular) Antibody 50 μl Polyclonal Antibodies
$695.00 Add Ask
4 Leading Biology APR03844G UBE2W Antibody (C-term) 100 μl Polyclonal Antibodies
$495.00 Add Ask
5 Leading Biology APR04349G HECTD2 Antibody (N-term) 100 μl Polyclonal Antibodies
$495.00 Add Ask
6 Leading Biology APR03502G IGHG1 Antibody (Center) 100 μl Polyclonal Antibodies
$495.00 Add Ask

This item has successfully been added to your cart!

You have 0 item in your cart

Your inquiry has successfully been added to your list!

You have 0 item in your inquiry list