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CRABP2 Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR04008G 100 μl / $495

CRABP2 Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR04008G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CRABP2 Antibody (C-term).

Molecular Weight

15693 Da

Cellular Localization

Antigen Cellular Localization: Cytoplasm. Endoplasmic reticulum. Nucleus. Note=Upon ligand binding, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus

Host

Rabbit

Species Reactivity

Human

Immunogen

87-116 aa

Target

This CRABP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-116 amino acids from the C-terminal region of human CRABP2.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.

Summary

A number of specific carrier proteins for members of the vitamin A family have been discovered. Cellular retinoic acid binding proteins (CRABP) are low molecular weight proteins whose precise function remains unknown. The inducibility of the CRABP2 gene suggests that this isoform is important in retinoic acid-mediated regulation of human skin growth and differentiation. It has been postulated that the CRABP2 gene is transcriptionally regulated by a newly synthesized regulatory protein. [provided by RefSeq].

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

CRABP2 Antibody (C-term) (Cat. APR04008G) western blot analysis MDA-MB453 cell line lysates (35ug/lane).This demonstrates the CRABP2 antibody detected the CRABP2 protein (arrow).

Western blot analysis of CRABP2 (arrow) using rabbit polyclonal CRABP2 Antibody (C-term) (Cat. APR04008G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the CRABP2 gene.

Specification

Quantity

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