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IL25 Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR03992G 100 μl / $495

IL25 Antibody (Center)

Brand

Leading Biology

Catalog Number

APR03992G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IL25 Antibody (Center).

Molecular Weight

20330 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human

Immunogen

76-104 aa

Target

This IL25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-104 amino acids from the Central region of human IL25.

Isotype

Rabbit Ig

Symbol

IL17E

GeneID

UniProt ID

Function

Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses.

Summary

The protein encoded by this gene is a cytokine that sharessequence similarity with interleukin 17. This cytokine can induceNF-kappaB activation, and stimulate the production of interleukin8. Both this cytokine and interleukin 17B are ligands for thecytokine receptor IL17BR. Studies of a similar gene in mice suggestthat this cytokine may be a pro-inflammatory cytokine favoring theTh2-type immune response. Alternative splicing results in multipletranscript variants.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Images

All lanes : Anti-IL25 Antibody (Center) at 1:1000 dilution Lane 1: human testis lysate Lane 2: PC-3 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 20 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

IL25 Antibody (Center) (Cat. APR03992G) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the IL25 antibody detected the IL25 protein (arrow).

IL25 Antibody (Center) (APR03992G)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of IL25 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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