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OSM Antibody (C-term)

Catalog # Availability Size / Price Inquiry
APR03969G 100 μl / $495

OSM Antibody (C-term)

Brand

Leading Biology

Catalog Number

APR03969G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality OSM Antibody (C-term).

Molecular Weight

28484 Da

Cellular Localization

Antigen Cellular Localization: Secreted.

Host

Rabbit

Species Reactivity

Human

Immunogen

214-243 aa

Target

This OSM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 214-243 amino acids from the C-terminal region of human OSM.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration (By similarity).

Summary

Oncostatin M is a member of a cytokine family thatincludes leukemia-inhibitory factor, granulocyte colony-stimulatingfactor, and interleukin 6. This gene encodes a growth regulatorwhich inhibits the proliferation of a number of tumor cell lines.It regulates cytokine production, including IL-6, G-CSF and GM-CSFfrom endothelial cells.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, E

Dilution

WB~~1:1000

Images

Western blot analysis of lysate from Jurkat cell line, using OSM Antibody (C-term)(Cat. APR03969G). APR03969G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.

Specification

Quantity

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