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IL9R Antibody (Center)

Catalog # Availability Size / Price Inquiry
APR03954G 100 μl / $495

IL9R Antibody (Center)

Brand

Leading Biology

Catalog Number

APR03954G

Product Type

Polyclonal Antibodies

Field of Research

Product Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IL9R Antibody (Center).

Molecular Weight

57147 Da

Cellular Localization

Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein. Secreted

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

170-199 aa

Target

This IL9R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-199 amino acids from the Central region of human IL9R.

Isotype

Rabbit Ig

GeneID

UniProt ID

Function

This is a receptor for interleukin-9.

Summary

The protein encoded by this gene is a cytokine receptorthat specifically mediates the biological effects of interleukin 9(IL9). The functional IL9 receptor complex requires this protein aswell as the interleukin 2 receptor, gamma (IL2RG), a common gammasubunit shared by the receptors of many different cytokines. Theligand binding of this receptor leads to the activation of variousJAK kinases and STAT proteins, which connect to different biologicresponses. This gene is located at the pseudoautosomal regions of Xand Y chromosomes. Genetic studies suggested an association of thisgene with the development of asthma. Multiple pseudogenes onchromosome 9, 10, 16, and 18 have been described. Alternativelyspliced transcript variants have been found for this gene.

Storage & Stability

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Applications

WB, IHC-P, E

Dilution

WB~~1:1000 IHC-P~~1:10~50

Images

Anti-IL9R Antibody (Center) at 1:1000 dilution + Jurkat whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 57 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

IL9R Antibody (Center) (APR03954G)immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of IL9R Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

Specification

Quantity

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